Table 3.

Logistic regression analysis for the association of marital status and stage at diagnosis in colorectal cancer patients.

	Stage at diagnosis (advanced vs. localized)a
	OR (95% CI)	P value
Marital status
Married	Reference	–
Unmarried	1.52 (1.33, 1.73)	< 0.0001
Gender
Female	Reference	–
Male	0.81 (0.74, 0.87)	< 0.0001
Age at diagnosis
18–39	1.20 (1.01, 1.45)	0.041
40–49	1.36 (1.78, 1.58)	< 0.0001
50–59	Reference	–
60–69	1.10 (0.98, 1.22)	0.09
70–98	0.95 (0.85, 1.11)	0.37
Pathological grading
Well differentiated	1.13 (0.90,1.40)	0.27
Moderately differentiated	Reference	–
Poorly differentiated	2.27 (1.85, 2.79)	< 0.0001
Unknown	0.93 (0.82, 1.10)	0.33
Morphology
Adenocarcinoma (AC), NOS	Reference	–
Mucin-producing AC	1.44 (0.95, 2.17)	0.083
Mucinous AC	1.39 (1.16, 1.67)	0.0003
Signet ring cell carcinoma	2.79 (1.16, 4.82)	0.0002
AC in villous/tubuvillous adenoma	0.38 (0.29, 0.49)	< 0.0001
Others	0.40 (0.33, 0.47)	< 0.0001
Chemotherapy
Yes	Reference	–
No	0.31 (0.28, 0.34)	< 0.0001
Surgery
Yes	Reference	–
No	2.10 (1.88, 2.23)	< 0.0001
Radiotherapy
Yes	Reference	–
No	0.81 (0.69, 0.96)	0.015

^aMultiple imputation-based analysis.