Table 3.
Clinical outcomes according to pre-existing depression.
| Multivariable analysis | Angina (n = 50,256) | AMI (n = 40,049) | ||
|---|---|---|---|---|
| Depression with Non-depression | Depression with Non-depression | |||
| In-hospital outcome | Odds ratio (95% confidence interval) | P-value | Odds ratio (95% confidence interval) | P-value |
| In-hospital mortality | 0.999 (0.758–1.318) | 0.996 | 1.100 (0.906–1.335) | 0.338 |
| Follow-up outcome | Hazard ratio (95% confidence interval) | P-value | Hazard ratio (95% confidence interval) | P-value |
| All-cause Death | 1.093 (0.992–1.024) | 0.074 | 1.107 (0.998–1.228) | 0.054 |
| Propensity score matching analysis | Angina (n = 4,262 pairs) | AMI (n = 2,346 pairs) | ||
|---|---|---|---|---|
| Depression with Non-depression | Depression with Non-depression | |||
| In-hospital outcome | Odds ratio (95% confidence interval) | P-value | Odds ratio (95% confidence interval) | P-value |
| In-hospital mortality | 1.232 (0.840–1.808) | 0.285 | 1.008 (0.870–1.168) | 0.919 |
| Follow-up outcome | Hazard ratio (95% confidence interval) | P-value | Hazard ratio (95% confidence interval) | P-value |
| All-cause Death | 1.013 (0.893–1.151) | 0.836 | 0.991 (0.865–1.136) | 0.901 |
| Propensity score matching analysis for AD medicated depression |
Angina (n = 3,524 pairs) | AMI (n = 1,868 pairs) | ||
|---|---|---|---|---|
| Depression with Non-depression | Depression with Non-depression | |||
| In-hospital outcome | Odds ratio (95% confidence interval) | P-value | Odds ratio (95% confidence interval) | P-value |
| In-hospital mortality | 1.000 (0.671–1.490) | 0.999 | 1.208 (0.934–1.563) | 0.150 |
| Follow-up outcome | Hazard ratio (95% confidence interval) | P-value | Hazard ratio (95% confidence interval) | P-value |
| All-cause Death | 1.122 (0.975–1.291) | 0.109 | 1.048 (0.900–1.220) | 0.544 |
AD Antidepressants, AMI acute myocardial infarction.