Table 1.
Total sample | MCI | HC | Group differences | ||
---|---|---|---|---|---|
(n = 32) | (n = 15) | (n = 17) | p-value | ||
Mean (SD) | Mean (SD) | Mean (SD) | |||
Demographics | |||||
Age (years) | 78.4 (6.8) | 80.5 (5.6) | 76.5 (7.0) | 0.10 | |
Female (n, %) | 0.16 | ||||
Education (years) | 16.0 (2.6) | 15.6 (3.1) | 16.5 (1.9) | 0.25 | |
APOE-ε4 Carriers | 12 | 5 | 5 | 0.81 | |
Cardiorespiratory fitness | |||||
Baseline VO2peak (ml/kg/min) | 19.9 (3.9) | 19.5 (5.2) | 19.1 (6.6) | 0.33 | |
Depression | |||||
Baseline GDS | 4.8 (3.3) | 5.3 (4.5) | 3.2 (2.0) | 0.007 | |
Cognition | Baseline DRS-2 | 134.1 (11.2) | 128.8 (13.3) | 140.5 (2.5) | 0.002 |
Activities of Daily Living | |||||
Baseline Lawton IADL | 4.7 (0.5) | 4.7 (0.5) | 4.7 (0.5) | 0.87 |
Notes: MCI, Mild Cognitive Impairment; HC, Healthy Control; APOE-ɛ4, apolipoprotein E epsilon 4 allele; VO2peak, peak rate of oxygen consumption in millimeters per kilogram per minute (ml/kg/min); GDS, Geriatric Depression Scale; DRS-2, Mattis Dementia Rating Scale-2; IADL, Instrumental Activities of Daily Living. Bold indicates p < 0.05.