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. 2021 Apr 8;9:638508. doi: 10.3389/fcell.2021.638508

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Copyright © 2021 Angrisani, Di Fiore, Di Trani, Fonte, Petroni, Lospinoso Severini, Bordin, Belloni, Ferretti, Canettieri, Moretti and De Smaele.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The human KCTD-containing Cullin3 Adaptor of Suppressor of Hedgehog 2 (KCASH2) proximal promoter. The Transcription Start Site (TSS) is identified with the asterisk and is considered as nucleotide number 1. The putative binding sequences for Sp1 and p53 TFs are named from A to H and A to B, respectively. The relative core sequences are highlighted in bold.