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. 2020 Jun 5;6(5):377–380. doi: 10.1016/j.ijwd.2020.06.001

Table 1.

Common conditions associated with lip-licking dermatitis, including typical clinical presentations, etiologies, and management.

Condition Clinical presentation Etiologies Management
Cheilitis simplex Dry, cracked vermillion lips; can be fissured or desquamated depending on severity Dry climates, habitual lip-licking, irritant exposure (saliva, topical acne medications, mechanical irritation) Prevention is key; apply bland lip balm frequently throughout the day for adequate moisturization; avoid possible irritants
Angular cheilitis Erythema and scaling of oral commissures, commonly associated with maceration Overexposure to saliva (drooling, medication side effect, chronic mouth breathing in allergic rhinitis), nutritional deficiencies, chronic medical conditions (diabetes, inflammatory bowel disease) Reduce moisture and treatment of underlying etiology; consider topical antifungal versus topical corticosteroid based on clinical presentation
Eczematous cheilitis Erythema and scaling of vermilion lips, with possible fissuring; may also involve cutaneous lip Most commonly associated with allergens, such as propolis, acrylates, nickel, cobalt, menthol, corticosteroids, preservatives, and fragrances Reduce lip care routine to sensitive (dye, fragrance free) products only; consider use of low-potency topical steroid twice daily for 1–2 weeks if needed; if persistent, consider patch testing
Exfoliative cheilitis Thick desquamative scale, most commonly along the vermilion border and involving the lower lip Unknown etiology in most cases; possible association with actinic damage, lip-licking, nutritional deficiencies, and body-focused repetitive behaviors Attempt to diagnose and treat underlying cause; treat secondary infections (if present)
Factitial cheilitis Cyclical peeling of keratinaceous scale, involving the vermilion lips Repetitive behaviors, such as lip-licking, biting, sucking, or picking Habit reversal techniques are the mainstay of management; consider cognitive behavioral therapy if associated with behavioral health condition