Figure 5.

Effect of MgIG on expression of Bax, Bcl-2, caspase-3 and cleaved caspase-3. (A) Western blotting was used to determine the expression levels of Bax, Bcl-2 and caspase-3. Intensity of (B) Bax, (C) caspase-3 and (D) Bcl-2 was standardized to protein expression levels of β-actin. (E) Western blotting analysis was performed to determine expression of cleaved caspase-3. (F) Intensity of cleaved caspase-3 was standardized to the protein expression levels of β-actin. Data are presented as the mean ± SEM (n=3). **P<0.01 vs. CON, ^#P<0.05 and ^##P<0.01 vs. ATO. MgIG, magnesium isoglycyrrhizinate; ATO, arsenic trioxide; CON, control.