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Mechanism of the protective effect of MgIG against hepatotoxicity induced by ATO. MgIG, magnesium isoglycyrrhizinate; ATO, arsenic trioxide; Keap1, Kelch-like ECH-associated protein 1; Nrf2, nuclear factor erythroid 2-related factor 2; CAT, catalase; SOD, superoxide dismutase; GSH, glutathione; MDA, malonaldehyde; ROS, reactive oxygen species.
