Figure 2. Association of Family Genetic Risk Score (FGRS) for Major Depression, Bipolar Disorder, and Schizophrenia With Age at First Registration and Number of Registrations.

Mean standardized FGRS and 95% CI were estimated from a linear regression model controlling for year of birth.

^aP for linear trend: major depression FGRS, <.001; bipolar disorder FGRS, <.001.

^bP for linear trend: bipolar disorder FGRS, .09; schizophrenia FGRS, .01.

^cP for linear trend: bipolar disorder FGRS, .93; schizophrenia FGRS, .08.