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| Creatinine clearance (mL/min) | Ceftolozane-tazobactam | Meropenem |
|---|---|---|
| > 50 | 3 g every 8 h | 1 g every 8 h |
| 30–50 | 1.5 g every 8 h | 1 g every 12 h |
| 15–29 | 750 mg every 8 h | 500 mg every 12 h |