Table 2.
Univariable competing risk analysis with the Fine–Gray model in 197 patients waiting for lung transplantation
| Characteristics | HR | 95% CI | p-value |
|---|---|---|---|
| Sex, male | 1.08 | 0.68–1.71 | 0.76 |
| Age, years | 1.04 | 1.02–1.06 | < 0.001 |
| BMI, kg/m2 | 1.00 | 0.94–1.05 | 0.90 |
| Smoking history | 1.01 | 0.64–1.62 | 0.96 |
| Charlson comorbidity index | 1.01 | 0.75–1.37 | 0.96 |
| Interstitial lung disease | 2.75 | 1.70–4.44 | < 0.001 |
| Long-term oxygen therapy | 0.80 | 0.43–1.52 | 0.50 |
| PaO2, mmHg | 1.01 | 1.00–1.02 | 0.14 |
| PaCO2, mmHg | 1.02 | 1.00–1.04 | 0.041 |
| FVC, L | 0.58 | 0.43–0.80 | < 0.001 |
| FVC, %predicted | 0.98 | 0.97–0.99 | < 0.001 |
| FEV1, L | 0.92 | 0.68–1.25 | 0.61 |
| FEV1, %predicted | 1.00 | 0.99–1.01 | 0.89 |
| 6-min walk distance, m | 1.00 | 1.00–1.00 | 0.55 |
| mMRC dyspnea | 1.46 | 1.13–1.87 | 0.003 |
| SGRQ symptoms | 1.02 | 1.01–1.04 | 0.0014 |
| SGRQ activities | 1.03 | 1.01–1.05 | 0.002 |
| SGRQ impacts | 1.03 | 1.02–1.04 | < 0.001 |
| SGRQ total | 1.04 | 1.02–1.05 | < 0.001 |
| HADS anxiety | 1.07 | 1.02–1.13 | 0.013 |
| HADS depression | 1.05 | 1.01–1.10 | 0.024 |
HR hazard ratio, CI confidence interval, BMI body mass index, PaO2 arterial partial pressure of oxygen, PaCO2 arterial partial pressure of carbon dioxide, FVC forced vital capacity, FEV1 forced expiratory volume in the first second, mMRC modified Medical Research Council, SGRQ St. George’s Respiratory Questionnaire, HADS Hospital Anxiety and Depression Scale