Table 1.

Therapy recommendations for EDS in adults

EDS in adult	Treatment	Dosage per day	FDA	EMA
First line	Modafinil	100–400 up to 600 mg	X	X
	Armodafinil	100 up to 250 mg	X
	Pitolisant	9up to 36 mg	X	X
	Sodium oxybate	4.5–9 g (split dose at night)	X
	Solriamfetol	75 up to 150 mg	X	X
Second line	Methylphenidate	10–40 up to 60 mg	X	X
	Dextroamphetamine			X
	Adderall	5 up to 60 mg		X
	Evekeo			X