Table 2.

Therapy recommendations for cataplexy in adults

Cataplexy in adults	Treatment	Dosage per day	FDA	EMA
First line	Sodium oxybate	4.5–9 g (split dose at night)	X	X
	Pitolisant	9 up to 36 mg	X	X
Second line	Venlafaxine	37.5 up to 225 mg
	Fluoxetine	10–20 up to 60 mg
	Citalopram	10–20 up to 40 mg
	Clomipramine	10–25 up to 75 mg