Table 3.

Therapy recommendations for EDS and cataplexy in children

Therapy for children	Treatment	Dosage per day	FDA	EMA
EDS	Modafinil	50 up to 400 mg
	Armodafinil	50 up to 400 mg
	Pitolisant	4.5 up to 36 mg
	Sodium oxybate	2–8 g (split dose at night)	X	X
	Methylphenidate	10 up to 40 mg
	Dextroamphetamine	2.5 up to 20 mg (twice a day)
Cataplexy	Sodium oxybate	2–8 g (split dose at night)	X	X
	Pitolisant	4.5 up to 36 mg
	Imipramine	10–100 mg
	Clomipramine	10–150 mg
	Protriptyline	2.5–5 mg
	Fluoxetine	10–30 mg
	Venlafaxine	3.75–75 mg