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. 2021 Feb;24(2):136–142. doi: 10.22038/ijbms.2020.48905.11208

Table 1.

Common gene cassette arrays in types of integrons in diverse bacterial species and their role in antimicrobial resistance

References Antibiotics associated with gene cassettes gene cassettes Integrons Bacteria
(28, 30) Aminoglycosides, Trimethoprim, Extended Spectrum Beta-Lactamase, Erythromycin. aadA1, aadA2, aadA5 aadB, dfrA1, dfrA5, dfrA7 dfrA12, dfr14, dfrA17, dfrB2, dfrA1-gcuC, dfrA1-aadA1, dfr17-aadA5,
dfr12-gcuF-aadA2, dfrA1-sat1-aadA1, dfrA1-sat2-aadA1, estX-sat2-aadA1,
blaOXA-101-aac (6')–Ib, ere2.
I, II, III Escherichia coli
(27, 32, 33) Extended Spectrum Beta-Lactamase, Aminoglycosides, Trimethoprim. blaCARB-2, aadA1, aadA2, aadB, dfrA1, dfrA7, dfrA1-gcuF, dfrA1- aadA1, dfr17-aadA5, dfr12-gcuF-aadA2, sat1. I, II Acinetobacterbaumannii
(27, 36) Aminoglycosides, Trimethoprim, Extended Spectrum Beta-Lactamase. aadA, aadA1a, aadA2, aadA5, aadB, dfrA1, dfrA7, dfrA12, dfrA17, dfrA1-gcuF, dfrA1-aadA1a, dfr17-aadA5, dfr12-gcuF-aadA2, blaCARB-2. I, II Salmonella spp.
(4, 27) Extended Spectrum Beta-Lactamase, Trimethoprim, Aminoglycosides, blaCARB-2 blaGES-1, aadA, aadA1, aadB, dfrA1, dfrA7, dfrA1-gcuF, dfrA1-aadA1a, dfr17-aadA5, dfr12-gcuF-aadA2. I, II, III Klebsiella spp.
(16) Aminoglycosides, Trimethoprim aadA2, aadB, dfr17-aadA5, dfr12-gcuF-aadA2. I Pseudomonas aeruginosa
(46) Aminoglycosides, Trimethoprim, Chloramphenicol aadA1, aadA2, dfr17-aadA5, dfr12-gcuF-aadA2, aacA4-cmlA1 I Staphylococcus aureus
(43) Aminoglycosides, Trimethoprim aadA1a, dfr12-gcuF-aadA2, dfrA1-sat1-aadA1. I Enterococcus faecalis
(44) Aminoglycosides, Trimethoprim aadA1a, aadA2, dfrA7, dfrA1-aadA1a, dfr17-aadA5, dfr12-gcuF-aadA I Enterobacter spp.