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TkoAGOG is the major 8oxoG BER enzyme. A, Deletion of TkoAGOG (open circles, dashed line) does not affect cellular growth compared to the parent strain TS559 (closed circles, solid line). B, Deletion of TkoAGOG does not result in any phenotypic difference following exposure to potassium bromate. C, Cleavage of dsDNA containing 8oxoG by T. kodakarensis cellular extracts. As a positive control, recombinant TkoAGOG was added to the ΔAGOG extract.
