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. Author manuscript; available in PMC: 2021 Apr 22.
Published in final edited form as: DNA Repair (Amst). 2019 Dec 5;86:102767. doi: 10.1016/j.dnarep.2019.102767

Fig. 6.

Fig. 6.

TkoAGOG and TkoEndoIV are both required to generate a 3’-OH from the site of an 8oxoG lesion. A, A 60-nt, 5’-FAM (blue), 3’-ROX (red) labeled dsDNA substrate with a centralized 8oxoG was incubated with either TkoAGOG, TkoEndoIV, or both TkoAGOG and TkoEndoIV at 65 °C and quenched with EDTA. B, Capillary electrophoresis traces highlighting the conversion of the 60-nt substrate to the 5’-FAM-labeled products, 3’-UA and 3’-OH after 30 min incubation with TkoAGOG and TkoEndoIV.