Skip to main content
. Author manuscript; available in PMC: 2021 Apr 22.
Published in final edited form as: DNA Repair (Amst). 2019 Dec 5;86:102767. doi: 10.1016/j.dnarep.2019.102767

Fig. 7.

Fig. 7.

Archaeal 8oxoG BER reconstituted in vitro. A, Schematic of the reaction products observed. B, Quantification of the amount of repaired product after 15 min. C, DNA substrates were pre-incubated with TkoAGOG and TkoEndoIV leaving a 3’-OH or a 3’-UA with a FAM (blue) label. DNA replication proteins were then added as shown on the left and incubated at 65 °C for 15 min. The repair was monitored by the appearance of the 60-nt dual-labeled FAM/ROX product (repaired) and the 60-nt FAM only labeled product (strand displaced).