Table 4.
Univariable and multivariable analysis of predictive factors related to overall survival
| Variable | Univariable | P‐value | Multivariable a | P‐value |
|---|---|---|---|---|
| Unadjusted HR (95% CI) | Adjusted HR (95% CI) | |||
| Age ≥ 65 years | 1.40 (0.95–2.04) | 0.86 | ||
| Severe 30 day postoperative complications Clavien–Dindo ≥ III b | 3.78 (2.48–5.75) | <0.001 | 2.82 (1.80–4.41) | <0.001 |
| ECOG > 1 | 3.38 (1.78–6.41) | <0.001 | 2.51 (1.25–5.03) | 0.01 |
| FIGO stage ≥ III A | 3.39 (2.04–5.63) | <0.001 | 2.61 (1.53–4.45) | <0.001 |
| Albumin < 35.5 g/L | 2.80 (1.71–4.58) | <0.001 | 2.15 (1.28–3.59) | 0.004 |
| Phase angle alpha < 4.5° | 3.10 (1.96–4.90) | <0.001 | 1.76 (1.07–2.90) | 0.03 |
| Nutritional Risk Screening 2002 ≥ 3 | 1.42 (0.97–2.07) | 0.07 | ||
| BMI ≥ 25–30 kg/m2 | 1.11 (0.57–2.17) | 0.76 | ||
| BMI > 30 kg/m2 | 1.01 (0.51–2.01) | 0.97 | ||
| Weight loss ≥ 10% last 3 months | 1.30 (0.72–2.31) | 0.39 | ||
| Extracellular mass to body cell mass index > 1.3 | 2.71 (1.74–4.24) | <0.001 | ||
| Fat mass > 39 kg | 1.45 (0.82–2.54) | 0.20 | ||
| Low hand grip strength | 1.30 (0.87–1.93) | 0.20 | ||
| Timed ‘Up and Go’ test > 11 s | 1.92 (1.09–3.37) | 0.02 | ||
| Muscle mass < 17 kg | 1.36 (0.71–2.62) | 0.35 | ||
| Skeletal muscle index ≤ 24.5% | 1.45 (0.90–2.32) | 0.13 |
BMI, body mass index; CI, confidence interval; ECOG PS, Eastern Cooperative Oncology Group performance status; FIGO, International Federation of Gynecology and Obstetrics; HR, hazard ratio.
a
Multivariable logistic regression analyses stepwise forward.