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. 2021 Feb 16;12(2):378–392. doi: 10.1002/jcsm.12680

Figure 1.

Figure 1

Plasma tissue inhibitor of metalloproteinases‐1 (TIMP‐1) levels differentiate subpopulations of weight loss (WL)‐defined cachectic colorectal cancer (CRC) patients. Survival of CRC patients (n = 80) separated by relative WL (A). Correlation of plasma TIMP‐1 levels with relative WL of CRC patients (n = 82) (B). Survival of CRC patients with increased WL (WLHI, n = 34) separated by plasma TIMP‐1 levels (C, cut‐off: 288.37 ng/mL TIMP‐1). Hazard ratios (HRs) are shown including the corresponding 95.0% confidence interval (A, C). Relative WL of WLHI CRC patients separated by plasma TIMP‐1 levels is shown as individual dots and medians with interquartile range (D).