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. Author manuscript; available in PMC: 2021 Jul 15.
Published in final edited form as: Sci Transl Med. 2020 Jul 15;12(552):eaaz7287. doi: 10.1126/scitranslmed.aaz7287

Fig. 1. M3mP6 HLPN.

Fig. 1.

(A) A schematic of lipid-stabilized, high-loading peptide nanoparticles (HLPN). (B) Structure of M3mP6 peptide. (C) Dose-dependent inhibitory effects of M3mP6 on the coimmunoprecipitation of integrin β3 and Gα13 in α-thrombin (0.025 U/mL) stimulated human platelets compared to scrambled peptide. (D) Quantification of coimmunoprecipitation blots in panel C (n=3). OD, optical density. (E) The size distribution of a single preparation of M3mP6 HLPN (6.6 ±0.8 nm) as analyzed by dynamic light scattering (43).