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. Author manuscript; available in PMC: 2021 Apr 22.
Published in final edited form as: Nat Rev Neurol. 2019 Mar;15(3):135–147. doi: 10.1038/s41582-018-0132-6

Figure 1 ∣. Amyloid plaques in Down syndrome.

Figure 1 ∣

Representative example of Aβ plaques (Aβ1-42; brown staining; arrowheads) and neurofibrillary tangles (PHF-1 antibody; blue staining; arrow) in the frontal cortex of a 46 year old person with DS and endstage AD.