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. Author manuscript; available in PMC: 2021 Apr 22.
Published in final edited form as: Nat Rev Neurol. 2019 Mar;15(3):135–147. doi: 10.1038/s41582-018-0132-6

Figure 2 ∣. Brain structural changes in Down syndrome.

Figure 2 ∣

Structural differences shown in coronal and sagittal sections from an MRI between a 46 year old person with DS without dementia (parts A and C ) and a person without DS ( parts b and d) highlighting structural differences in frontal cortex (arrowhead in parts a and b), cerebellum (arrow in parts a and b) and hippocampus (arrow in parts c and d).