Table 3.

Clinical presentation of cutaneous malignancies in renal transplant recipients

Tumour	Clinical presentation
Squamous cell carcinoma (most frequent skin cancer in transplant recipients)	Enlarging, raised, keratotic (often ulcerated) lesions on an indurated, erythematous base. It has a high risk of local and distant spread and recurrence
Keratoacanthoma	Solitary firm dome-shaped tumor on sun-exposed skin. Due to the central keratin core, it is referred to as “crateriform” lesion. It can undergo ulceration.
Basal cell carcinoma	Flesh-colored pearly papule with a characteristic rolled-out beaded margin, often with central ulceration and overlying telangiectasias. It is a locally aggressive malignancy, with rare chances of metastases
Melanoma	Development of a new pigmented lesion or recent-onset change in colour, shape or size of a pigmented skin lesion is the most sensitive clinical sign for melanoma.
Merkel cell carcinoma	Usually presents as pink-red to violaceous, firm, dome-shaped solitary nodule that has rapidly grown; shows prediliction for head and neck region of older adults and demonstrates aggressive malignant behaviour.
Kaposi sarcoma	Cutaneous lesions vary from pink patches to dark violet plaques, nodules, or polyps, depending on clinical variant and stage.