Table 1.
Baseline Characteristics.a
| Overall, N = 171b | Gram negative, n = 67 | Gram positive, n = 46 | Culture negative, n = 47 | P Value | |
|---|---|---|---|---|---|
| Demographics | |||||
| Age (years)c | 62(14) | 62 (15) | 65 (13) | 59 (12) | .1152d |
| Sex: male | 96 (56.1) | 36 (53.7) | 26 (56.5) | 27 (57.5) | .916e |
| Female | 75 (43.9) | 31 (46.3) | 20 (43.5) | 20 (42.6) | |
| Race: black | 85 (49.7) | 35 (52.2) | 19 (41.3) | 26 (55.3) | .490e |
| White | 84 (49.1) | 32 (47.8) | 26 (56.5) | 20 (42.6) | |
| Other | 2(1.2) | 0 | 1 (2.17) | 1 (2.13) | |
| Initial vital signs | |||||
| Systolic blood pressure (mm Hg)c | 116 (33) | 111 (30) | 120 (38) | 113 (31) | .3645d |
| Heart rate (beats/min) c | 108 (26) | 107 (27) | 107 (24) | 106 (28) | .9885d |
| Respiratory rate (breaths/min)f | 20 (18–26) | 20 (18–26) | 20 (18–26) | 20 (18–22) | .6885g |
| Temperature (°F)f | 99 (98–101) | 99 (99–102) | 98 (98–101) | 99 (98–101) | .0446g |
| SpO2 (%)f | 97 (94–99) | 97 (94–99) | 96 (93–98) | 97 (93–99) | .6091g |
| Comorbidities & indwelling line status | |||||
| Statin use | 67 (39.4) | 25 (37.3) | 20 (43.5) | 19 (40.4) | .838e |
| Chronic obstructive pulmonary disease | 31 (18.1) | 11 (16.4) | 9 (19.6) | 9 (19.2) | .811e |
| Diabetes mellitus | 75 (43.9) | 26 (38.8) | 18 (41.3) | 23 (48.9) | .549e |
| Human immunodeficiency virus status | 8(4.7) | 5 (7.5) | 1 (2.2) | 2 (4.3) | .539h |
| End-stage renal disease | 20 (11.7) | 11 (16.4) | 4 (8.7) | 5 (10.6) | .471h |
| Active cancer | 17 (9.9) | 8 (11.9) | 5 (10.9) | 3 (6.4) | .674h |
| Organ transplant | 3(1.8) | 2 (3.0) | 0 (0) | 1 (2.1) | .784h |
| Indwelling vascular Catheter | 7(4.1) | 4 (6.0) | 2 (4.4) | 1 (2.1) | .803h |
Abbreviations: ANOVA, analysis of variance; IQR, interquartile range; SpO2, peripheral capillary oxygen saturation.
a
Data are counts and (percentages), unless otherwise specified.
b
Eleven patients with mixed growth cultures excluded from between group analyses (N = 160 for comparisons).
c
Mean (standard deviation).
d
ANOVA.
e
χ2.
f
Median (IQR).
g
Kruskal-Wallis.
h
Fisher exact.