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Protein S-palmitoylation and regulation. Palmitoylation-depalmitoylation cycle regulates protein-membrane association, lipid raft targeting, protein stability and protein–protein interactions, among others. Dynamic S-palmitoylation is mediated by DHHC palmitoyl acyl transferases (DHHC-PATs) and depalmitoylases. Image created with Biorender.com.
