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. 2021 Apr 22;433(13):167003. doi: 10.1016/j.jmb.2021.167003

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Reversibility of GC376 with SARS-CoV M^pro and SARS-CoV-2 M^pro. The dependence of activity of SARS-CoV M^pro (A) and SARS-CoV-2 M^pro (B) incubated alone and with the bound GC376 compound on time. Data are presented as mean ± SEM, n = 3.