Table 6:
Spearman’s rho correlations (p-value) of Pre-OMM control faecal sample microbiota to constipation and PD severity and symptoms scales. Measure of PD severity quantified by each UPDRS subscale: Part 1: Non-Motor Aspects of Experiences of Daily Living; Part 4: Motor Complications.
| Phylum | UPDRS Total | H&Y | 4.6 | Mobility Gait and Posture | PAQ-QOL |
|---|---|---|---|---|---|
| Actinobacteria | −.270 (.604) | −.859 (.028)* | −.502 (.310) | −.464 (.354) | −.878 (.021)* |
| Bacteroidetes | −.243 (.643) | .347 (.501) | −.144 (.786) | −.106 (.842) | .867 (.025)* |
| Euryarchaeota | .895 (.016)* | .494 (.320) | .390 (.444) | .736 (.096) | −.128 (.810) |
| Fibrobacteres | .963 (.002)* | .523 (.287) | .441 (.381) | .789 (.062) | −.143 (.788) |
| Proteobacteria | .541 (.268) | −.246 (.638) | −.292 (.575) | .058 (.225) | −.426 (.400) |
| Synergistetes | .841 (.036)* | .452 (.368) | .385 (.451) | .704 (.118) | −.175 (.740) |
| Verrucomicrobia | .481 (.334) | .645 (.167) | .870 (.024)* | .834 (.039)* | −.129 (.807) |
| Firmicutes | −.155 (.769) | −.592 (.216) | −.180 (.734) | −.348 (.499) | −.678 (.139) |
Abbreviations: UPDRS: Unified PD Rating Scale; PAC: Patient Assessment Constipation; SYM: Symptoms.
p ≤ .05;
p < .01.
UPDRS questions Mobility, Gait, and Posture {2.11 Getting out of bed, a car, or a deep chair (0 – 4); 2.12 Walking and balance (0 – 4); 2.13 Freezing (0 – 4); 3.3 Rigidity (0 – 4); 3.9 Arising from chair (0 – 4); 3.10 Gait (0 – 4); 3.11 Freezing of gait (0 – 4); 3.12 Postural stability (0 – 4); 3.13 Posture (0 – 4)); and 4.6 Painful off-state dystonia}.