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. 2021 Apr 22;16(4):e0250611. doi: 10.1371/journal.pone.0250611

Table 3. Clinical outcomes of early adjunctive corticosteroids therapy after anti-pneumocystis therapy initiation (all patients).

Naïve survival analysis IPW survival analysis
Variable Effect size 95% CI p-value Effect size 95% CI p-value
30-days mortalitya 2.04 [1.02–4.09] 0.04 1.45 [0.7–3.04] 0.32
1-year mortalitya 1.85 [1.17–2.91] 0.008 1.25 [0.75–2.09] 0.39
SOFA resp worseningb 1.01 [0.87–1.18] 0.87 0.68 [0.27–1.71] 0.42
Intubation day-5b 0.96 [0.84–1.1] 0.56 0.45 [0.12–1.6] 0.22
Coinfectionsb 1.1 [0.93–1.31] 0.28 0.89 [0.41–1.91] 0.77

IPW = Inverse Probability Weighting

a Hazard Ratio

b Odd ratio. SOFA = Sequential Organ Failure Assessment Score, SOFA resp = respiratory SOFA.