Table 3. Clinical outcomes of early adjunctive corticosteroids therapy after anti-pneumocystis therapy initiation (all patients).
Naïve survival analysis | IPW survival analysis | |||||
---|---|---|---|---|---|---|
Variable | Effect size | 95% CI | p-value | Effect size | 95% CI | p-value |
30-days mortalitya | 2.04 | [1.02–4.09] | 0.04 | 1.45 | [0.7–3.04] | 0.32 |
1-year mortalitya | 1.85 | [1.17–2.91] | 0.008 | 1.25 | [0.75–2.09] | 0.39 |
SOFA resp worseningb | 1.01 | [0.87–1.18] | 0.87 | 0.68 | [0.27–1.71] | 0.42 |
Intubation day-5b | 0.96 | [0.84–1.1] | 0.56 | 0.45 | [0.12–1.6] | 0.22 |
Coinfectionsb | 1.1 | [0.93–1.31] | 0.28 | 0.89 | [0.41–1.91] | 0.77 |
IPW = Inverse Probability Weighting
a Hazard Ratio
b Odd ratio. SOFA = Sequential Organ Failure Assessment Score, SOFA resp = respiratory SOFA.