Table 2.
Fixed-effects model-based pooled-SIR estimates and 95% CIs of kidney cancer cases associated with asbestos exposure by incidence study characteristics.
| Study characteristics | No. of studies | Pooled-SIR (95% CI) | Q | P Q | I 2 (%) |
|---|---|---|---|---|---|
| All | 11 | 0.95 (0.79–1.11) | 7.47 | 0.68 | 0.0 |
| Type of asbestos | |||||
| Chrysotile | 3 | 0.93 (0.47–1.39) | 0.39 | 0.83 | 0.0 |
| Amphibole | 4 | 0.83 (0.57–1.09) | 4.39 | 0.22 | 31.7 |
| Undefined | 4 | 1.04 (0.82–1.26) | 1.25 | 0.74 | 0.0 |
| Industry type | |||||
| Mining | 2 | 1.10 (0.60–1.60) | 0.84 | 0.36 | 0.0 |
| Cement | 4 | 0.93 (0.62–1.23) | 0.39 | 0.94 | 0.0 |
| Mixed | 3 | 1.03 (0.81–1.26) | 1.17 | 0.56 | 0.0 |
| Others | 2 | 0.53 (0.09–0.98) | 0.78 | 0.38 | 0.0 |
| Cohort size | |||||
| <5000 | 8 | 0.82 (0.56–1.08) | 5.72 | 0.57 | 0.0 |
| ≥5000 | 3 | 1.02 (0.82–1.22) | 0.32 | 0.85 | 0.0 |
| Follow-up period | |||||
| <25 years | 5 | 0.93 (0.73–1.13) | 5.83 | 0.21 | 31.4 |
| ≥25 years | 6 | 0.97 (0.71–1.24) | 1.57 | 0.90 | 0.0 |
| Person-years follow-up | |||||
| <100 000 person-years | 5 | 0.74 (0.45–1.03) | 3.66 | 0.46 | 0.0 |
| ≥100 000 person-years | 4 | 1.03 (0.83–1.23) | 0.41 | 0.94 | 0.0 |
| No data | 2 | 1.20 (0.53–1.88) | 0.27 | 0.60 | 0.0 |
| NOS rating | |||||
| Good | 11 | 0.95 (0.79–1.11) | 7.47 | 0.68 | 0.0 |
| Geographic location | |||||
| Europe | 8 | 0.93 (0.76–1.10) | 7.16 | 0.41 | 2.3 |
| Asia | 2 | 1.10 (0.29–1.90) | 0.06 | 0.81 | 0.0 |
| Australia | 1 | 1.03 (0.51–1.56) | 0 | NA | NA |
I 2, I2 statistic; NA, not applicable; PQ, P value for Cochran Q test; Q, Cochran Q test.