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. 2021 Apr 22;16(4):e0249584. doi: 10.1371/journal.pone.0249584

Table 3. Neonatal characteristics and outcomes.

Feature Positive mother Positive neonate (N = 9) Positive mother Negative neonate (N = 21) Negative Mother Negative neonate (N = 9) P
No. (%)
Gestational age at birth 0.496
<34 1 (11) 1 (5) 2 (22)
34–36 3 (33) 4 (19) 2 (22)
>37 5 (56) 16 (76) 5 (56)
Median, range, w 38.2, 28–39.5 38.2, 29–41.6 37.1, 32.2–40.4
Missing data 0 0 0
Birth weight 0.340
<1500 1 (11) 1 (5) 2 (22)
1500–2499 3 (33) 3 (14) 2 (22)
>2500 5 (56) 17 (81) 5 (56)
Median, range, g 2850, 1050–4038 3170, 1050–3905 2696, 1275–3720
Missing data 0 0 0
Birth weight for gestational age 0.042*
Appropriate-for-gestational-age 3 (33)a 17 (81)b 7 (78)a,b
Small-for-gestational-age 4 (44) 4 (19) 2 (22)
Large-for-gestational-age 2 (22) 0 0
Missing data 0 0 0
Sex 0.682
Female 4 (50) 11 (52) 3 (8)
Male 4 (49) 10 (48) 6 (15)
Undetermined 1 0 0
Missing data 0 0 0
Apgar at minute 1 0.896
1–3 0 1 (5) 0
4–6 2 (22) 2 (9) 1 (12)
7–9 7 (78) 18 (86) 7 (87)
Missing data 0 0 1
Apgar at minute 5: 0.660
1–3 0 1 (5) 0
7–9 9 (100) 20 (95) 8 (100)
Missing data 0 0 1
Antenatal glucocorticoid 3 (33) 2 (9) 2 (22) 0.303
Missing data 0 0 0
Reanimation: 0.168
None 4 (44) 9 (43) 1 (11)
Oxygen 1 (11) 8 (38) 5 (56)
Oxygen+CPAP 2 (22) 1 (5) 2 (22)
Oxygen+Face mask ventilation+CPAP 1 (11) 3 (14) 1 (11)
Oxygen+Face mask ventilation+ETT ventilation 1 (11) 0 0
Missing data 0 0 0
Surfactant 1 (11) 0 0 Omitted
Missing data 0 0 0
Admitted to NICU 4 (44)a 1 (5)b 2 (22)a,b 0.031*
Missing data 0 0 0
Ventilation: 0.224
None 6 (15) 15 (71) 4 (44)
Oxygen 0 4 (19) 3 (33)
Conventional mechanical ventilation 1 (11) 0 0
Continuous Positive Airway Pressure 2 (22) 2 (9) 2 (22)
High Frequency Ventilation 0 0 0
Missing data 0 0 0
Respiratory morbidities: 0.024*
None 6 (67)a,b 20 (95)a 5 (56)b
Transitory Tachypnea 0 0 1 (11)
Respiratory Distress Syndrome 2 (22) 1 (5) 2 (22)
Tachypnea 0 0 1 (11)
Pulmonary Hypertension 1 (11) 0 0
Missing data 0 0 0
Gastrointestinal morbidities: Omitted
None 8 (88) 21 (100) 9 (100)
NEC 1 (1) 0 0
Missing data 0 0 0
Malformations: Omitted
CNS 0 1 (5) 0
Multiple (CNS, urogenital, cardiac) 1 (11) 1 (5) 0
Missing data 0 0 0
Days at hospital: <0.001*
1–2 5 (56)a,b 18 (90)a 4 (44)b
3–6 0 2 (10) 3 (33)
>7 4 (44)a 0b 0a,b
Median, range, d 2, 1–23 2, 0–3 2, 1–4
Missing data 0 1 2
Final Outcome: 0.702
Discharged at home 8 (89) 18 (90) 5 (55)
Discharged to hospital 0 1 (5) 0
Still admitted 0 1 2 (6)
Died 1 (11) 1 (5) 2 (6)
Missing data 0 0 0
Feeding at discharge: 0.066
Fasting 0 1 (5) 0
Human milk 5 (62) 12 (63) 5 (71)
Human milk + Formula 3 (37)a 0b 1 (14)a,b
Formula 0 6 (32) 1 (14)
Missing data 1 2 2

Each subscript letter denotes a subset of pregnant women category whose column proportions do not differ significantly from each other at the P<0.05 level in crosstab analysis.

* P<0.05.