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. 2021 Apr 22;16(4):e0249988. doi: 10.1371/journal.pone.0249988

Table 1. Characteristics of patient with thyroid-associated ophthalmopathy from whom orbital fibroblasts were obtained.

TAO Patient number Age Sex Smoking Grave’s disease Grave’s disease treatment TAO treatment Euthyroid state TSH receptor antibody CAS
Radioactive Iodine Methimazole Thyroidectomy Surgery Prednisolone Radiation
#103 23 F No Yes No Yes No Yes No No Yes + 2
#107 50 F No Yes No Yes No Yes Yes Yes Yes + 3
#110 65 M No Yes No No Yes Yes Yes No Yes + 1
#120 56 M Yes Yes No Yes No Yes Yes No Yes + 3
#135 61 M No Yes No Yes No Yes Yes No Yes + 1
#137 59 F No Yes No Yes No Yes Yes No Yes + 3
#162 73 F No Yes No Yes No Yes Yes No Yes + 3

All patients with TAO had experienced at least 6 months of inactive disease status with a euthyroid hormonal condition.

Non-TAO patients; #71 (female, 61 years), #111 (female, 68 years), #116 (male, 60 years), #136 (male, 59 years), #150 (female, 65 years), #152 (female, 22 years), #155 (male, 70 years), #158 (male, 75 years).

CAS, clinical activity score; TSH, thyroid-stimulating hormone.