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. 2021 Apr 22;16(4):e0249934. doi: 10.1371/journal.pone.0249934

Table 1. Antigen specificity of the immunodominant DSA in patients with DSA positive with Labscreen SAB and negative with Lifecodes SAB.

Antigen specificity of the dn DSA Nb of KTR MFI (OL) BCM (IM) BCR (IM) AD-BCR (IM)
A2 1 1600 99 1.2 1.19
A3 1 1300 35 0.32 0.33
B37 1 5802 0 0 0
B8 1 2400 206 0.83 0.75
DQ2 3 1017–3750–8882 312–0–0 1.13–0–0 1.3–0–0
DQ5 4 1556–2000–2443–10957 35-292-13-82 0.86–3.21–2.33–1.64 0.45–3.02–2.07–1.79
DQ6 1 5500 0 0 0
DQ7 3 1608–1980–2000 0-167-202 0–1.96–1.92 0–1.85–1.80
DR13 1 1924 0 0 0

KTR: kidney transplantation recipents; dn DSA: de novo donor specific antibody; iDSA: immunodominant DSA; MFI: mean fluorescence intensity; OL: One Lambda. SAB: single antigen beads; IM: Immucor; BCM: background corrected MFI; BCR: BCM divided by the raw MFI of the lowest ranked bead for a locus; AD-BCR: antigen density corrected BCR values.