Table 1. Antigen specificity of the immunodominant DSA in patients with DSA positive with Labscreen SAB and negative with Lifecodes SAB.
Antigen specificity of the dn DSA | Nb of KTR | MFI (OL) | BCM (IM) | BCR (IM) | AD-BCR (IM) |
---|---|---|---|---|---|
A2 | 1 | 1600 | 99 | 1.2 | 1.19 |
A3 | 1 | 1300 | 35 | 0.32 | 0.33 |
B37 | 1 | 5802 | 0 | 0 | 0 |
B8 | 1 | 2400 | 206 | 0.83 | 0.75 |
DQ2 | 3 | 1017–3750–8882 | 312–0–0 | 1.13–0–0 | 1.3–0–0 |
DQ5 | 4 | 1556–2000–2443–10957 | 35-292-13-82 | 0.86–3.21–2.33–1.64 | 0.45–3.02–2.07–1.79 |
DQ6 | 1 | 5500 | 0 | 0 | 0 |
DQ7 | 3 | 1608–1980–2000 | 0-167-202 | 0–1.96–1.92 | 0–1.85–1.80 |
DR13 | 1 | 1924 | 0 | 0 | 0 |
KTR: kidney transplantation recipents; dn DSA: de novo donor specific antibody; iDSA: immunodominant DSA; MFI: mean fluorescence intensity; OL: One Lambda. SAB: single antigen beads; IM: Immucor; BCM: background corrected MFI; BCR: BCM divided by the raw MFI of the lowest ranked bead for a locus; AD-BCR: antigen density corrected BCR values.