Table 4. Top causal inference test results for meQTLs of SS DMRs.
| SNP rs ID | SNP position | A1 | A2 | SS DMR | distance | p.cit | q.cit |
|---|---|---|---|---|---|---|---|
| rs9275224 | 32659878 | G | A | chr6:32810706–32810742 | 150828 | 1.00E-3 | 2.11E-3 |
| rs9275224 | 32659878 | G | A | chr6:32819921–32820102 | 160043 | 1.00E-3 | 2.11E-3 |
| rs9275224 | 32659878 | G | A | chr6:32822911–32823116 | 163033 | 1.00E-3 | 2.11E-3 |
| rs9275224 | 32659878 | G | A | chr6:32813084–32813337 | 153206 | 1.00E-3 | 2.11E-3 |
| rs9275224 | 32659878 | G | A | chr6:32813448–32813531 | 153570 | 1.00E-3 | 2.11E-3 |
| rs2261033 | 31603591 | G | A | chr6:31544694–31544931 | 58660 | 1.17E-3 | 2.11E-3 |
| rs2261033 | 31603591 | G | A | chr6:31527920–31528239 | 75352 | 1.89E-3 | 2.11E-3 |
| rs2734985 | 29818662 | G | A | chr6:30042980–30042985 | 224318 | 1.99E-3 | 2.11E-3 |
| rs9275374 | 32668526 | A | G | chr6:32810706–32810742 | 142180 | 3.99E-3 | 3.47E-3 |
| rs2261033 | 31603591 | G | A | chr6:31539973–31539998 | 63593 | 5.25E-3 | 4.17E-3 |
| rs13335209 | 87860446 | A | C | chr16:87636539–87636594 | 223852 | 5.78E-3 | 4.30E-3 |
| rs3021302 | 32623150 | G | A | chr6:32810706–32810742 | 187556 | 7.84E-3 | 4.89E-3 |
| rs3021302 | 32623150 | G | A | chr6:32819921–32820102 | 196771 | 1.47E-2 | 9.29E-3 |
| rs2858332 | 32681161 | C | A | chr6:32819921–32820102 | 138760 | 1.63E-2 | 1.05E-2 |
| rs17407659 | 24238010 | A | G | chr12:24104007–24104115 | 133895 | 1.74E-2 | 1.35E-2 |
| rs3021302 | 32623150 | G | A | chr6:32813084–32813337 | 189934 | 2.49E-2 | 1.64E-2 |
| rs3021302 | 32623150 | G | A | chr6:32822911–32823116 | 199761 | 2.69E-2 | 1.74E-2 |
| rs2858332 | 32681161 | C | A | chr6:32810706–32810742 | 129545 | 3.36E-2 | 2.14E-2 |
| rs76027985 | 112439220 | G | A | chr3:112359488–112359557 | 79663 | 3.65E-2 | 2.44E-2 |
All genetic positions are based on GRCh37 coordinates, and DMRs are denoted by the chromosome, start position, and end position. Distance refers to base pair distance between DMR and meQTL. A1 = allele 1; A2 = allele 2; SS DMR = differentially-methylated regions for Sjögren’s syndrome; p.cit = causal inference test p-value; q.cit = permutation-based q-values from the causal inference test.