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. 2021 Mar 26;10:e63642. doi: 10.7554/eLife.63642

Figure 1. Type I and type II microbial oxalate-degrading pathway (ODP).

(A) Schema of type I and type II ODP. Enzymes are annotated with corresponding KEGG IDs. OXDD, FRC, and OXC are the focus of the present study. (B). Cladogram of microbial genera that encode oxalate-degrading enzymes OXDD, FRC, and OXC. The three rings surrounding the cladogram indicate OXDD-, FRC-, or OXC-encoding genera, respectively.

Figure 1.

Figure 1—figure supplement 1. Inter-class and intra-class ODE protein identity associated with each microbial class.

Figure 1—figure supplement 1.

Panels focus on OXDD (A), OXC (B), or FRC (C). The pairwise identity between any two protein homologs was calculated based on the multiple alignments using amino acid sequences, by Fitch, 1966 or identity distance matrix (see Materials and methods for details). The number of ODE homologs available for each class is indicated in parenthesis. Classes with >20 ODE are shown.