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. 2021 Mar 19;40(16):2858–2871. doi: 10.1038/s41388-021-01729-1

Table 1.

TMCC3 silencing of AS-B145 and AS-B634 reduces their tumor-initiating capacitiesa.

(Cell number of injection) Stem cell frequency p value
105 5 × 104 104 103 102 50
AS-B145 shControl 5/5 5/6 3/5 1:19,707 0.014
shTMCC3 4/5 3/7 1/5 1:70,682
AS-B634 shControl 8/8 5/5 4/5 3/5 1:59 <0.001
shTMCC3 8/8 3/5 1/5 0/5 1:987

aBCSC-enriched population of AS-B145 and AS-B634 were infected with shTMCC3 #B or shControl and injected into mammary fat pads of NSG mice.