Table 2.

Association of risk factors with recurrence and survival of breast cancer in univariate and multivariable analysis.

Variables	RFS						OS
	Univariate analysis			Multivariable analysis			Univariate analysis			Multivariable analysis
	HR	95% CI	p value	HR	95% CI	p value	HR	95% CI	p value	HR	95% CI	p value
Age: ≥50 vs <50	2.74	1.43–5.24	0.002	2.54	1.32–4.89	0.005	2.66	1.42–4.96	0.002	2.35	1.25–4.43	0.008
Grade: III vs I + II	1.89	1.04–3.46	0.038				1.89	1.06–3.40	0.032
Stage: III + IV vs I + II	1.74	0.94–3.23	0.08				2.81	1.62–4.89	0.001	2.38	1.36–4.17	0.002
ER: (+) vs (−)	0.63	0.36–1.08	0.09				1.13	0.65–1.97	0.66
PR: (+) vs (−)	0.59	0.34–1.03	0.06				0.79	0.45–1.38	0.40
HER2: (+) vs (−)	0.86	0.49–1.50	0.59				0.88	0.51–1.51	0.64
TMCC3 Tumor: high vs low	3.32	1.89–5.83	0.001	2.81	1.45–5.45	0.002	2.92	1.69–5.02	0.001	2.28	1.31–3.96	0.004

RFS relapse-free survival, OS overall survival, HR hazard ratio, CI confidence interval.

Bold values indicate statistical significance p < 0.05.