Table 2.
Prognostic performance of PDGFRb score group in uni- and multivariable Cox regression analysis
Endpoint | PDGFRb score group | Univariable HR (95% CI); p value | Multivariable incl. RT, grade, age group, subtype HR (95% CI); p value |
---|---|---|---|
IBTR, 10 years | Low | 1 | 1 |
Medium | 1.51 (0.99–2.30); 0.057 | 1.44 (0.92–2.62); 0.111 | |
High | 1.33 (0.87–2.02); 0.187 | 1.20 (0.77–1.89); 0.423 | |
Any recurrence, 10 years | Low | 1 | 1 |
Medium | 1.58 (1.11–2.23); 0.011 | 1.46 (1.01–2.11); 0.042 | |
High | 1.49 (1.06–2.10); 0.021 | 1.32 (0.93–1.88); 0.125 | |
BCSD, 15 years | Low | 1 | 1 |
Medium | 1.37 (0.85–2.21); 0.191 | 1.24 (0.77–2.01); 0.381 | |
High | 1.52 (0.96–2.38); 0.075 | 1.26 (0.79–2.01); 0.333 |
p values are based on Wald test; p values < 0.05 in bold text
IBTR ipsilateral breast tumor recurrence, BCSD breast cancer specific death, RT radiotherapy, HR hazard ratio, CI confidence interval