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. 2021 Apr 22;11:8727. doi: 10.1038/s41598-021-88158-y

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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A ground truth simulated L-COSY spectrum is shown (top). Sampling schemes were applied to the simulated spectrum using the sampling masks shown in the 1st column. These masks sampled 25, 50, and 75 $t_{1}$ points out of a total 100 $t_{1}$ points to yield 4x, 2x, and 1.3x acceleration factors, respectively. The 2nd column shows the under-sampled spectra in the ( $F_{2}, F_{1}$ ) domain and the 3rd column shows the spectra reconstructed using a D-UNet model. Errors for each reconstruction are displayed as difference maps in the final column.