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. 2021 Apr 22;11:8727. doi: 10.1038/s41598-021-88158-y

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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The mean squared error is displayed as a function of noise level for the quantitation D-UNet results (left). These results were produced by analyzing MSE for 100 identical spectra at 10 different noise levels ranging from 0 to 25% noise relative to the maximum signal intensity. Two example spectra are shown displying 5% noise (middle) and 20% noise (right). Qualitatively, it is clear that cross-peak signal amplitude is greatly altered due to the added noise in the noise level = 8 spectrum.