Skip to main content
. 2021 Apr 22;11:8731. doi: 10.1038/s41598-021-87917-1

Table 2.

Vital signs, clinical symptoms, and morbidities in patients with different disease severities.

Feature Disease severity P1 P2***
Mild/moderate (N = 33) Severe (N = 139) Critical (N = 28)
Vital signs
Pulse rate 87.12 ± 20.12 94.71 ± 26.64 106.48 ± 26.36 0.003**  < 0.001
Respiratory rate 20.12 ± 1.97 26.64 ± 6.87 26.36 ± 6.76  < 0.001**  < 0.001
BP (mmHg) 126.71 ± 21.98 126.74 ± 15.42 129.68 ± 23.68 0.478** 0.467
Temperature (°C) 37.63 ± 0.65 37.65 ± 0.66 37.98 ± 0.83 0.742** 0.084
O2 saturation (%) 95.48 ± 1.25 87.80 ± 6.37 82.15 ± 10.00  < 0.001**  < 0.001
Symptoms
Fever 23 (69.7) 101 (72.7) 19 (67.9) 0.802* 0.849
Dyspnea 24 (72.7) 123 (88.5) 24 (85.7) 0.023* 0.069
Nausea/vomiting 11 (33.3) 22 (15.8) 4 (14.3) 0.016* 0.055
Cough 29 (87.9) 129 (92.8) 25 (89.3) 0.414* 0.595
Diarrhea 8 (24.2) 19 (13.7) 2 (7.1) 0.082* 0.148
Conjunctivitis 0 (0.0) 2 (1.4) 0 (0.0) 0.528* 0.642
Myalgia 16 (48.5) 69 (49.6) 15 (53.6) 0.849* 0.914
Arthralgia 7 (21.2) 18 (12.9) 2 (7.1) 0.156* 0.261
Weakness 16 (48.5) 65 (46.8) 14 (50.0) 0.901* 0.945
Abdominal pain 1 (3.0) 6 (4.3) 0 (0.0) 0.872* 0.519
Seizure 0 (0.0) 1 (0.7) 0 (0.0) 0.656* 0.802
Headache 3 (9.1) 26 (18.7) 2 (7.1) 0.266* 0.164
Sore throat 1 (3.0) 19 (13.7) 2 (7.1) 0.109* 0.167
Chill 10 (30.3) 28 (20.1) 7 (25.0) 0.240* 0.428
Hyposmia 4 (12.1) 11 (7.9) 2 (7.1) 0.414* 0.710
Fatigue 9 (27.3) 40 (28.8) 7 (25.0) 0.919* 0.916
Confusion 0 (0.0) 2 (1.4) 3 (10.7) 0.517* 0.043
Rhinorrhea 1 (3.0) 3 (2.2) 0 (0.0) 0.802* 0.681
Morbidities
Shock 0 (0.0) 1 (0.7) 6 (21.4) 0.231*  < 0.001
Sepsis 0 (0.0) 1 (0.7) 8 (28.6) 0.172*  < 0.001
ARDS 0 (0.0) 1 (0.7) 27 (96.4) 0.011*  < 0.001
DHF 0 (0.0) 1 (0.7) 0 (0.0)  > 0.999* 0.802
ATN 0 (0.0) 1 (0.7) 1 (3.6)  > 0.999* 0.288
Coagulopathy 0 (0.0) 0 (0.0) 1 (3.6)  > 0.999* 0.046
Acidosis 0 (0.0) 0 (0.0) 1 (3.6)  > 0.999* 0.046
ICU admission 0 (0.0) 0 (0.0) 14 (50.0) 0.085*  < 0.001
Intubation 0 (0.0) 0 (0.0) 23 (82.1) 0.023*  < 0.001

BP blood pressure, ARDS acute respiratory distress syndrome, DHF diastolic heart failure, ATN acute tubular necrosis, ICU intensive care unit.

P1: Comparison between mild/moderate and severe/critical groups.

P2: Comparison between mild/moderate, severe, and critical groups.

Bold values are statistically significant (P < 0.05).

*Chi-square or Fisher’s exact test.

**Mann–Whitney test.

***Kruskal–Wallis test.