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. 2021 Apr 22;11:8728. doi: 10.1038/s41598-021-87908-2

Table 1.

Computational stent modeling studies.

References Aim Stent designs Vessel model Performance metric
Samant et al. (current study) Study computationally and experimentally the performance of novel Everolimus-eluting stent designs

MEGATRON 9-, 10- and 12-peak designs and SYNERGY

(Boston Scientific)

Patient-specific left main bifurcations with homogeneous wall (spectrum of very soft to very stiff) and patient-specific heterogeneous wall

Stent expansion

Vessel scaffolding

Vessel prolapse

Stent-artery ratio

Normalized hoop force/ Radial strength

Bobel et al.12 Assess the performance of biodegradable stents MultiLink, Absorb (Abbott) and Igaki–Tamai (Kyoto Medical Planning Co.) Parallel network viscoelastic material model

Radial stent strength

Stent Flexibility

Longitudinal stent resistance

Ragkousis et al.17 Assess the longitudinal integrity of first and second-generation drug eluting stents in a patient-specific coronary artery segment Promus element, Promus element modified, (Boston Scientific) Xience (Abbott), and Cypher (Johnson and Johnson Co.) Patient-specific straight coronary artery segment with homogeneous wall

Longitudinal stent deformation

Stent malapposition

Roy et al.25 Computational performance of various commercially available stent designs Palmaz Schatz, Cypher (Cordis, J & J), S670, Driver (Medtronic,), Taxus Express, Element (Boston Scientific) Free stent expansion (without vessel) Von Misses stresses
Chiastra et al.24 Computational fluid dynamic studies in stented coronary models Xience Prime (Abbott) and Endeavor Resolute (Medtronic) Patient-specific coronary bifurcation lumen with idealized homogeneous wall Computational fluid dynamic studies
Boyle et al.26 Long term restenosis outcomes of different stent designs on mechanobiological model of arterial tissue MultiLink (Abbott), Palmaz (Johnson and Johnson Co.), and Inflow (Inflow Dynamics) Idealized vessel models Neointimal tissue growth
Conway et al.18 Assess the performance of different designs in straight and curved vessels Cypher (Johnson and Johnson Co.) and MultiLink (Abbott) Idealized straight and curved arterial models with homogeneous wall

Vessel recoil after stenting

Vessel scaffolding

von Mises stresses

Grogan et al.19 Study the performance of bio-absorbable stents Generic and alloy-specific stent designs of magnesium, iron, steel and cobalt-chromium Free stent expansion (without vessel)

Radial stent strength

Stent recoil

Stent flexibility

Longitudinal stent resistance

von Mises stresses

Principal logarithmic stent strain

Mortier et al.20 Evaluate the mechanical behavior of different stent platforms Integrity (Medtronic), Veriflex (Boston Scientific), MultiLink 8 (Abbott), Multi-Link Vision (Abbott Vascular), Pro-Kinetic Energy (Biotronik), and Promus Element (Boston Scientific) Idealized non-bifurcated vessel models with homogeneous wall

Stent malapposition

Vessel wall stresses

Wu et al.21 Optimize the shape of biodegradable magnesium alloy stents Four different variation of magnesium alloy stent compared to the existing Magic (Biotronik) Idealized straight vessel with homogeneous wall

Vessel scaffolding

Stent recoil

Maximum principal stress and strain

Gijsen et al.23 Study stent deployment in patient-specific coronary artery segment Bx velocity (Cordis, Johnson and Johnson) Patient-specific straight coronary artery segment with homogeneous wall Luminal and stent stresses
Migliavacca et al.22 Assess the mechanical stent performance of different stent designs

Palmaz-Schatz, MultiLink Tetra (Guidant) and Carbostent

(Sorin Biomedica)

Free stent expansion (without vessel)

Radial and longitudinal stent recoil

Stent foreshortening

Etave et al.27 Determine mechanical characteristics of different stent designs Palmaz-Schatz (Johnson and Johnson Co.) and Freedom (Global Therapeutics Inc.) Free stent expansion (without vessel)

Elastic recoil

Longitudinal and radial stent resistance

Vessel Scaffolding

Stent flexibility

Stress maps