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. 2021 Apr 22;11:234. doi: 10.1038/s41398-021-01347-1

Fig. 4. PF-4778574 rescues sex social behavioral deficits in A350V Iqsec2 mice.

Fig. 4

A Mean investigation time summed separately for the Female and Male stimuli throughout the SxP test, conducted by WT mice 2 days after vehicle injection. B Mean investigation time summed separately for the Female and Male stimuli throughout the SxP test conducted by A350V mice 1–2 days after either vehicle (left, n = 26) or PF-4778574 (right, n = 26) injection. C As in B, for the SxP test conducted by A350V mice 7–8 days after either vehicle (left, n = 12) or PF-4778574 (right, n = 26) injection. D Mean investigation time summed separately for the Isolated and Grouped stimuli in the ESP test conducted by WT mice 2 days after vehicle injection. E Mean investigation time summed separately for the Isolated and Grouped stimuli in the ESP test conducted by A350V mice 1–2 days after either vehicle (left, n = 12) or PF-4778574 (right, n = 26) injection. F As in E, for the ESP test conducted by A350V mice 7–11 days after either vehicle (left, n = 12) or PF-4778574 (right, n = 26) injection. *p < 0.05, **p < 0.01, paired t-test following the main effect in ANOVA test. All error bars represent SEM.