Fig. 1.

Serial analyses of log-transformed N-terminal pro-B-type natriuretic peptide (logNT-proBNP) levels throughout pregnancy in women with cardiovascular (CV) complications (black line, n = 7) and without CV complications (grey line, n = 119). Absolute NT-proBNP levels at 10–14, 20–24 and 30–34 weeks are reported as median (Q1–Q3). ^aReported as median (minimum-maximum). A significant difference in the course of logNT-proBNP was found between women with CV complications and without CV complications (p < 0.001). NT-proBNP levels decreased after 10–14 weeks’ gestation in women without CV complications and remained high in women with CV complications