Table 3.

Associations between log-transformed N-terminal pro-B-type natriuretic peptide, age and cardiac function at first trimester

	n	Beta	95% CI	p-value
Age	126	0.044	0.013–0.075	0.005
NYHA class	126	0.379	0.041–0.718	0.028
LVEDD/BSA	99	0.044	−0.008–0.096	0.100
LVESD/BSA	92	0.033	−0.016–0.083	0.187
LAVi	50	0.023	−0.010–0.055	0.163
LVEF	103	−0.037	−0.059–−0.016	0.001
TAPSEa	104	−0.054	−0.080–−0.029	<0.001
S’ RVa	74	−0.059	−0.113–−0.005	0.034
E/A ratio	86	0.286	−0.069–0.641	0.113
E’	75	0.021	−0.042–0.084	0.515
Multivariable regression analysesa,b
Age	126	0.054	0.018–0.089	0.004
TAPSE	104	−0.060	−0.087–−0.033	<0.001

BSA body surface area, CI confidence interval, E ’early diastolic tissue Doppler velocity of systemic ventricular annular ring, E/A ratio early to atrial mitral inflow velocity ratio, LAVi indexed systemic atrial volume, LVEDD systemic ventricular end-diastolic diameter, LVEF systemic ventricular ejection fraction, LVESV systemic ventricular end-diastolic diameter, NYHA New York Heart Association, S’ systolic tissue Doppler velocity of subpulmonary ventricular annular ring, TAPSE tricuspid annular plane systolic excursion

^aWomen with systemic right ventricle excluded from analyses

^bDegrees of freedom = 72