Table 4.

Univariate and multivariate analysis of the stroke, bleeding, and other endpoints.

Clinical outcomes	Univariate			Multivariate
	OR	95% CI	P-value	OR	95% CI	P-value
Primary endpoint
Stroke history	3.000	1.063~8.468	0.038	3.000	1.063~8.468	0.038
SEC	3.032	1.011~9.098	0.048
Stroke events
Platelet count	1.015	1.002~1.029	0.022	1.015	1.002~1.029	0.022
DRT
Platelet count	1.014	1.001~1.027	0.032
Stroke history	11.583	1.263~106.198	0.030	23.509	1.261~438.351	0.023
PDL	8.467	0.926~77.389	0.058	17.005	1.008~286.902	0.049
LAA flow velocity	0	0~0.073	0.025
Overall bleeding events
Platelet count	0.990	0.980~1.000	0.041
Thrombocytopenia	6.330	2.172~18.471	0.001	8.150	2.579~25.757	<0.001
HAS-BLED score	1.957	1.129~3.392	0.017	2.307	1.254~4.243	0.007
Bleeding history	3.311	1.111~9.868	0.032
Major bleeding
HAS-BLED	2.200	1.107~4.373	0.024	2.441	1.177~5.061	0.016
Thrombocytopenia	3.667	0.972~13.832	0.055	4.571	1.133~18.438	0.033

SEC, spontaneous echo contrast; DRT, device-related thrombus; PDL, peri-device leak; LAA, left atrial appendage.