Table 1.
Baseline characteristics of patients hospitalized with COVID-19.
| Overall (n = 1,128) | Critically Ill (n = 350) | Not Critically Ill (n = 778) | P-value, Critically ill vs. Not Critically Ill | |
|---|---|---|---|---|
| DEMOGRAPHICS, N (%) | ||||
| Age, median [IQR] | 59 [45, 73] | 65.00 [53, 77] | 56.00 [42, 70] | <0.001* |
| 18–29 | 59 (5.2) | 7 (2.0) | 52 (6.7) | |
| 30–39 | 125 (11.1) | 22 (6.3) | 103 (13.2) | |
| 40–49 | 168 (14.9) | 42 (12.0) | 126 (16.2) | |
| 50–59 | 227 (20.1) | 63 (8/0) | 164 (21.1) | |
| 60–69 | 207 (18.4) | 76 (21.7) | 131 (16.8) | |
| 70–79 | 177 (15.7) | 72 (20.6) | 105 (13.5) | |
| 80–89 | 129 (11.4) | 55 (15.7) | 74 (9.5) | |
| ≥ 90 | 36 (3.2) | 13 (3.7) | 23 (3.0) | |
| Sex | 0.003* | |||
| Female | 488 (43.3) | 128 (36.6) | 360 (46.3) | |
| Male | 640 (56.7) | 222 (63.4) | 418 (53.7) | |
| Race | ||||
| African American or Black | 137 (12.1) | 44 (12.6) | 93 (12.0) | 0.845 |
| Asian | 41 (3.6) | 13 (3.7) | 28 (3.6) | 1.000 |
| White | 467 (41.4) | 147 (42.0) | 320 (41.1) | 0.835 |
| Latinx Ethnicity | 401 (35.5) | 110 (31.4) | 291 (37.4) | 0.008* |
| Tobacco Use | <0.001* | |||
| Never | 645 (57.2) | 168 (48.0) | 477 (61.3) | |
| Former | 218 (19.3) | 81 (23.1) | 137 (17.6) | |
| Present | 96 (8.5) | 25 (7.1) | 71 (9.1) | |
| Not asked | 45 (4.0) | 10 (2.9) | 35 (4.5) | |
| MEDICAL COMORBIDITIES, N (%) | ||||
| Charlson Comorbidity Index Score, mean (SD) | 1.53 (2.24) | 1.83 (2.47) | 1.39 (2.12) | 0.002* |
| 0 comorbidities | 562 (49.8) | 157 (44.9) | 405 (52.1) | |
| 1–2 comorbidities | 307 (27.2) | 93 (26.6) | 214 (27.5) | |
| ≥ 3 comorbidities | 259 (23.0) | 100 (28.6) | 159 (20.4) | 0.008* |
| Hypertension | 362 (32.1) | 121 (34.6) | 241 (31.0) | 0.260 |
| Diabetes | 204 (18.1) | 72 (20.6) | 132 (17.0) | 0.170 |
| Myocardial infarction | 33 (2.9) | 14 (4.0) | 19 (2.4) | 0.213 |
| Congestive heart failure | 115 (10.2) | 46 (13.1) | 69 (8.9) | 0.037* |
| Chronic obstructive pulmonary disease | 154 (13.7) | 49 (14.0) | 103 (13.5) | 0.893 |
| Renal disease | 113 (10.0) | 52 (14.9) | 61 (7.8) | <0.001* |
| Peripheral vascular disease | 87 (7.7) | 41 (11.7) | 46 (5.9) | 0.001* |
| Body Mass Index, median [IQR] | 28.8 [25.3, 33.3] | 28.9 [25.3, 34.1] | 28.8 [25.2, 32.9] | 0.450 |
| NEUROLOGIC COMORBIDITIES, N (%) | ||||
| Cerebrovascular comorbidities | 177 (15.7) | 69 (19.7) | 108 (13.9) | 0.016* |
| Acute Ischemic Stroke | 112 (9.9) | 49 (14.0) | 63 (8.1) | 0.016* |
| Venous Sinus Thrombosis | 4 (0.4) | 3 (0.9) | 1 (0.1) | 0.173 |
| Subarachnoid Hemorrhage | 5 (0.4) | 3 (0.9) | 2 (0.3) | 0.358 |
| Subdural Hemorrhage | 60 (5.3) | 18 (5.1) | 42 (5.4) | 0.973 |
| Intracerebral Hemorrhage | 22 (2.0) | 11 (3.1) | 11 (1.4) | 0.087 |
| Other neurological comorbidities | ||||
| Dementia | 39 (3.5) | 15 (4.3) | 24 (3.1) | 0.398 |
| Movement disorder | 28 (2.5) | 10 (2.9) | 18 (2.3) | 0.737 |
| Neuromuscular disorder | 56 (5.0) | 22 (6.3) | 34 (4.4) | 0.222 |
| Seizure history | 25 (2.2) | 6 (1.7) | 19 (2.4) | 0.583 |
| Brain tumor | 8 (0.7) | 1 (0.3) | 7 (0.9) | 0.451 |
*
indicates a p < 0.05. Charlson Comorbidity Index Score includes acute myocardial infarction, congestive heart failure, peripheral vascular disease, cerebrovascular disease, dementia, chronic obstructive pulmonary disease, rheumatoid disease, peptic ulcer disease, liver disease, diabetes with and without complications, hemiplegia or paraplegia, renal disease, cancer, metastatic solid tumor, and HIV/AIDS.