Table 2.
Hazards ratios and 95% confidence intervals of quintiles of dietary quality indices and all-cause mortality
| Dietary index | Range | Model 1a | Model 2b | Model 3c | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| (n = 3660) |
(n = 3506) |
(n = 3471) |
|||||||||||
| Events | PT, y | HR (95% CI) | HR (Ptrend) | Events | PT, y | HR (95% CI) | HR (Ptrend) | Events | PT, y | HR (95% CI) | HR (Ptrend) | ||
| ACS | 0.93 (<.001) | 0.96 (.04) | 0.96 (.07) | ||||||||||
| Q1 | 0-3 | 237 | 11 792.3 | Referent | 232 | 11 271.5 | Referent | 226 | 11 148.5 | Referent | |||
| Q2 | 4 | 128 | 5954.7 | 1.00 (0.81 to 1.25) | 124 | 5746.4 | 1.00 (0.80 to 1.25) | 122 | 5683.9 | 1.02 (0.81 to 1.27) | |||
| Q3 | 5 | 99 | 5363.6 | 0.80 (0.64 to 1.02) | 98 | 5211.6 | 0.90 (0.71 to 1.15) | 95 | 5172.1 | 0.90 (0.71 to 1.16) | |||
| Q4 | 6 | 96 | 4639.8 | 0.84 (0.66 to 1.07) | 93 | 4425.8 | 1.01 (0.78 to 1.29) | 92 | 4409.8 | 1.03 (0.80 to 1.33) | |||
| Q5 | 7-9 | 95 | 5817.2 | 0.67 (0.53 to 0.85) | 87 | 5516.2 | 0.73 (0.56 to 0.95) | 86 | 5466.2 | 0.77 (0.59 to 1.01) | |||
| aMED | 0.91 (<.001) | 0.96 (.10) | 0.97 (.27) | ||||||||||
| Q1 | 0-2 | 177 | 7349.3 | Referent | 171 | 7011 | Referent | 170 | 6908.0 | Referent | |||
| Q2 | 3 | 116 | 5628.9 | 0.84 (0.67 to 1.07) | 114 | 5425.2 | 1.07 (0.84 to 1.36) | 111 | 5380.1 | 1.08 (0.85 to 1.39) | |||
| Q3 | 4 | 119 | 5983.4 | 0.83 (0.65 to 1.05) | 114 | 5743.0 | 1.02 (0.79 to 1.30) | 112 | 5694.5 | 1.05 (0.82 to 1.35) | |||
| Q4 | 5 | 117 | 5584.4 | 0.87 (0.68 to 1.11) | 113 | 5401.7 | 1.13 (0.87 to 1.46) | 107 | 5346.2 | 1.17 (0.90 to 1.53) | |||
| Q5 | 6-9 | 126 | 9021.7 | 0.56 (0.43 to 0.71) | 122 | 8590.6 | 0.79 (0.61 to 1.03) | 121 | 8551.5 | 0.87 (0.66 to 1.14) | |||
| DASH | 0.96 (<.001) | 0.98 (.049) | 0.98 (.10) | ||||||||||
| Q1 | 10-20 | 131 | 5751.9 | Referent | 127 | 5536.3 | Referent | 124 | 5490.4 | Referent | |||
| Q2 | 21-23 | 187 | 9440.6 | 0.82 (0.66 to 1.03) | 184 | 9062.5 | 0.93 (0.74 to 1.18) | 180 | 8965.2 | 0.94 (0.75 to 1.19) | |||
| Q3 | 24-25 | 119 | 5772.7 | 0.78 (0.61 to 1.00) | 117 | 5541.5 | 0.96 (0.74 to 1.24) | 114 | 5450.4 | 1.00 (0.77 to 1.31) | |||
| Q4 | 26-27 | 95 | 4455.1 | 0.78 (0.60 to 1.02) | 88 | 4240.9 | 0.99 (0.74 to 1.31) | 87 | 4225.9 | 1.02 (0.77 to 1.36) | |||
| Q5 | 28-37 | 123 | 8147.4 | 0.53 (0.42 to 0.68) | 118 | 7790.2 | 0.76 (0.58 to 1.00) | 116 | 7748.6 | 0.80 (0.61 to 1.05) | |||
| HEI | 0.98 (<.001) | 0.99 (.04) | 0.99 (.12) | ||||||||||
| Q1 | 42.1-63.2 | 131 | 6104.4 | Referent | 127 | 5841.8 | Referent | 124 | 5741.9 | Referent | |||
| Q2 | 63.3-69.2 | 131 | 6019.3 | 1.01 (0.79 to 1.28) | 130 | 5859.8 | 0.85 (0.66 to 1.10) | 127 | 5815.7 | 0.85 (0.66 to 1.10) | |||
| Q3 | 69.3-73.9 | 131 | 6494.9 | 0.88 (0.69 to 1.12) | 128 | 6241.0 | 0.94 (0.73 to 1.20) | 124 | 6196.6 | 0.94 (0.73 to 1.22) | |||
| Q4 | 74.0-79.9 | 131 | 7411.4 | 0.74 (0.58 to 0.94) | 125 | 7068.9 | 0.77 (0.60 to 1.00) | 124 | 7010.1 | 0.82 (0.63 to 1.06) | |||
| Q5 | 80.0-95.4 | 131 | 7537.7 | 0.64 (0.51 to 0.82) | 124 | 7160.0 | 0.77 (0.60 to 1.01) | 122 | 7116.0 | 0.81 (0.62 to 1.06) | |||
a
Adjusted for age at diagnosis and total energy. ACS = American Cancer Society nutrition guidelines score; aMED = alternate Mediterranean Diet score; CI = confidence interval; DASH = Dietary Approaches to Stop Hypertension score; HEI = Healthy Eating Index score; HR = hazard ratio; PT = person-time; Q = quintile.
b
Adjusted for age at diagnosis, total energy, race and ethnicity, education, menopausal status, physical activity, smoking, cancer stage, estrogen-receptor status, progesterone-receptor status, and HER2.
c
Adjusted for all variables in model 2, plus body mass index, surgery type, chemotherapy, radiation, and hormonal therapies.