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. 2021 Apr 9;12:616050. doi: 10.3389/fmicb.2021.616050

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Copyright © 2021 Bednarz, Millan-Oropeza, Kotowska, Świat, Quispe Haro, Henry and Pawlik.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Proteomic analysis of S. coelicolor A3(2) wild-type (M145) and mutant strains. (A) Protein identifications in the analyzed strains. (B) Quantification of 489 proteins showing significant abundance change between the strains (ANOVA test, adjusted p value <0.01); methods: XIC, extracted ion chromatograms; SC, spectral count; PC, peak count. (C) Global heatmap representation of protein abundances with significant abundance change in function of the different strains (ANOVA test, adjusted p value <0.01). The method of quantification of each protein is indicated in colors on the left of the heatmap for extracted ion chromatogram (black), spectral count (orange) or peak count (cyan).