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Correlations between HBsAg and intrahepatic replication markers before NA discontinuation. Correlation between HBsAg and (A) iHBV-DNA, (B) iHBV-RNA, and (C) iHBV-RNA/cccDNA ratio as a measure of cccDNA transcriptional activity. Rho, Spearman’s correlation coefficient. #Data available for 18 patients. cccDNA, covalently closed circular DNA; iHBV-DNA, intrahepatic HBV-DNA; iHBV-RNA, intrahepatic HBV-RNA; NA, nucleos(t)ide analogue.
