Table 2.
Baseline characteristics of included patients
| Patient characteristics | |
|---|---|
| Number of eligible patients | 42 |
| Age, median (IQR), year | 59.4 (47.9–69.2) |
| Sex, no. (%) | |
| Male | 27 (64) |
| Female | 15 (35) |
| Weight, median (IQR), kg | 74.0 (65.0–88.5) |
| Body mass index, median (IQR), kg/m2 | 25.6 (21.8–30.8) |
| Obesity (BMI ≥ 30), no. (%) | 11 (27) |
| Comorbidities, no. (%) | |
| Diabetes | 8 (19) |
| Chronic obstructive pulmonary disease | 4 (9) |
| Immuno-incompetence | 13 (31) |
| Cardiac failure | 8 (19) |
| Liver failure | 15 (35) |
| End-stage renal disease | 3 (7) |
| Home oxygen/ventilation | 1 (2) |
| Location before ICU admission, no. (%) | |
| Other hospital ward | 19 (45) |
| Emergency room | 15 (35) |
| Other ICU | 8 (19) |
| Reason for ICU admission, no. (%) | |
| Cardiovascular/respiratory (e.g. cardiogenic, septic-shock) | 35 (83) |
| Liver failure | 7 (16) |
| Surgical status at ICU admission, no. (%) | |
| Scheduled surgery | 1 (2) |
| Emergency surgery | 5 (11) |
| No surgery | 36 (85) |
| SAPS 3 at ICU admission, median (IQR) | 74.0 58.8–84.0 |
| Duration of CVVH therapy, median (IQR), hours | 215 (101–398) |
| Pre-switch | 66 (38–156) |
| Post-switch | 111 (45–335) |
| Respiratory status during study period, no. (%) | |
| Mechanical ventilation during whole study period | 20 (48) |
| Mechanical ventilation intermittently during study period | 12 (29) |
| No mechanical ventilation | 9 (21) |
| Study participation, median (IQR), hours | 114 (84–144) |
| ICU stay, median (IQR), days | 19 (10–29) |
| Hospital stay, median (IQR), days | 40 (23–63) |
| Mortality, no./total no. (%) | |
| ICU | 12/42 (28.6) |
| Hospital | 19/42 (45.2) |